Magnetic Flocculation Of Cu(II) Wastewater By Chitosan-Based Magnetic Composite Flocculants With Recyclable Places

In this study, three magnetic flocculants, namely, MC, MC-g-PAM, and MC-g-PAA, were cooked. The structure features, flocculation performance, and floc characteristics of the three magnetic flocculants were systematically studied and equated FT-IR, XPS, XRD, TG-DSC, and VSM characterization issues show that MC, MC-g-PAM, and MC-g-PAA are successfully prepared and exhibit good magnetic induction. The removal rates of copper ions by MC, MC-g-PAM, and MC-g-PAA under the optimal coagulation conditions are 93 %, 88 %, and 61 %, respectively. Kinetic fitting shows that the flocculation reaction process of MC and MC-g-PAM adjusts to pseudo first-order kinetics, while the flocculation reaction process of MC-g-PAA adapts to pseudo second-order kinetics.  fucose benefits  growed by MC-g-PAA have larger particle size and fractal dimension than those by MC and MC-g-PAM. At 80 mg/L dosage and pH 6, the floc size and floc fractal dimension geted by MC-g-PAA reach the maximum values of 48 um and 1, respectively.

Zeta potential bailiwicks show that the flocculation functions of the three flocculants are mainly adsorption bridging, adsorption electric neutralization, and chelating precipitation. Recycling experiments show that MC-g-PAA has good recyclability, and the recovery rate after the fifth use is 77 % with the Cu(II) removal rate of 67 %.Self-assembling chitosan grinded injectable and expandable sponge with antimicrobial property for hemostasis and wound healing.Chitosan and chitosan derivative are widely used in hemostasis, antibiosis and wound repair for its good biocompatibility and unique effect the preparation of chitosan finded hemostatic textiles or wound fertilizations generally postulates chemical crosslinking agent introduction, acid residue or complicated preparation process, which fixs its clinical application. In this study, an injectable and expandable chitosan sponge was reconstructed by chitosan (CS) and quaternized chitosan (QCS) self-assembly without acid retention and chemical crosslinker introduction. In the neutral condition, the hydrogen bond of CS particles can act as the aiming force to form cross-linking network, and the QCS was introduced to regulate the hydrogen bond of CS to avoid the excessive aggregation. The porous QCS/CS sponge was obtained by freeze-drying of the self-assembly QCS/CS hydrogel.

The sponge displayed high expansibility, injectability and water/blood actuated shape memory property. Due to the introduction of QCS, the sponge ushered good antibacterial properties, which can protect the wound from bacterial invasion. The convenient and green preparation method of injectable and expandable QCS/CS sponge is a potential method for the treatment of hemostasis and wound healing.Optimizing gefitinib nanoliposomes by Box-Behnken design and coating with chitosan: A sequential approach for heightened drug delivery.BACKGROUND AND PURPOSE: This study proposed to improve the stability and sustained gefitinib release from the nanoliposomes. EXPERIMENTAL APPROACH: Nanoliposomes were educated by reverse-phase evaporation and optimized employing Box-Behnken design to investigate the influence of sonication time (X (1)), tween 80 / soya phosphatidylcholine ratio (X (2)), and cholesterol/soya phosphatidylcholine ratio (X (3)) on nanoliposomes. KEY RESULTS: optimised nanoliposomes were quasi-spherical shaped, with a mean dimension of 93 nm and an encapsulation efficiency of 87±0 %.

Surface decoration of the optimized batch was done using different compactnessses of chitosan. The optimal chitosan concentration required to adorn the nanoliposome surface was 0 %. In comparison to unadorned nanoliposomes (82±0 %), graced nanoliposomes (78±0 %) released the drug consistently over 24 h via Fickian diffusion. The IC(50) values for surface-invested nanoliposomes in A549 and H1299 cellphones were 6±0 and 4±0 μM, respectively. Cytotoxicity of the surface-ornamented nanoliposomes may be due to their higher zeta potential and prolonged drug release. At the end of the sixth month, the samples stored at 4 °C were more stable than those stored at 25 °C and 45 °C.